Communication between corneal epithelial cells and trigeminal neurons is facilitated by purinergic (P2) and glutamatergic receptors.

Previously, we demonstrated that nucleotides released upon mechanical injury to corneal epithelium activate purinergic (P2) receptors resulting in mobilization of a Ca(2+) wave.However, the tissue is extensively innervated and communication between epithelium and neurons is critical and not well understood.Therefore, we developed a co-culture of pr

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Quantitation of non-derivatized free amino acids for detecting inborn errors of metabolism by incorporating mixed-mode chromatography with tandem mass spectrometry

Introduction: Amino acids are critical biomarkers for many inborn errors of metabolism, but Jeans amino acid analysis is challenging due to the range of chemical properties inherent in these small molecules.Techniques are available for amino acid analysis, but they can suffer from long run times, laborious derivatization, and/or poor resolution of

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Detecting Winter Cover Crops and Crop Residues in the Midwest US Using Machine Learning Classification of Thermal and Optical Imagery

Cover crops are an increasingly popular practice to improve agroecosystem resilience to climate change, pests, and other stressors.Despite their importance for climate mitigation and soil health, there remains an urgent need for methods that link winter cover crops with regional-scale climate mitigation and adaptation potential.Remote sensing is id

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Changes in the pitch-accent system of Gernika Basque

The pitch-accent system in Northern Bizkaian Basque (NBB) is characterized for making a pitch distinction between lexical accented/unaccented words (i.e.singular vs.plural contrast) and for lacking a durational correlate of accentual prominence.The present study examines whether such system is maintained jeff rosenstock buffalo in Gernika Basque, a

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